- Author:
Chang Hee KIM
1
;
Jung Eun SHIN
;
Hee Joung KIM
;
Kye Young LEE
Author Information
- Publication Type:Case Report
- Keywords: Vertigo; Internal auditory canal; Neoplasm metastasis; Lung neoplasms; Hearing loss
- MeSH: Brain; Carcinoma, Non-Small-Cell Lung*; Complementary Therapies; Drug Therapy; Epidermal Growth Factor; Female; Hearing Loss; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Metastasis*; Phosphotransferases; Tinnitus; Vertigo
- From:Cancer Research and Treatment 2015;47(1):110-114
- CountryRepublic of Korea
- Language:English
- Abstract: We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitus for three months. The patient had refused all treatments, including surgery and chemotherapy; however, she sought alternative medicine. The patient's hearing loss showed rapid progression bilaterally, and rotatory vertigo with peripheral-type nystagmus developed. Magnetic resonance imaging of the brain showed irregular nodular enhancement within both internal auditory canals with leptomeningeal enhancement and multiple intracranial metastasis. The patient was treated with epidermal growth factor receptor-tyrosine kinase inhibitor, and the tumor showed partial response. This was a rare case of multiple brain metastases involving bilateral internal auditory canal from known NSCLC presenting with vertigo and hearing loss.