Extracellular matrix of the human retinal pigment epithelial cells in vitro.

Author: Myung Kyoo KO ¹ ; Joon Kiu CHOE
Author Information

1. Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.
Publication Type:Original Article
Keywords: extracellular matrix; retinal pigment epithelium; fibronectin; type IV collagen
MeSH: Cells, Cultured; Collagen/*analysis; Extracellular Matrix/*analysis/immunology; Fibronectins/*analysis; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Pigment Epithelium of Eye/*analysis
From:Korean Journal of Ophthalmology 1988;2(2):66-68
CountryRepublic of Korea
Language:English
Abstract: This study was undertaken to localize fibronectin and type IV collagen in the cultured retinal pigment epithelial cell by means of immunofluorescent staining and immunocytochemical methods. Immunofluorescent staining and immunocytochemical methods revealed fibronectin and type IV collagen localized on the extracellular membrane of the cultured retinal pigment epithelial cell. Ultrastructural immunocytochemical technique also revealed fibronectin associated with extracellular tissue. This study demonstrated that fibronectin and type IV collagen are an integral component of the extracellular matrix of the human retinal pigment epithelial cell in vitro.