A Clinical Study and the Histamine Test in Patients with Herpes Zoster.
- Author:
Yean Sub JANG
;
Jong Min KIM
;
Eil Soo LEE
- Publication Type:Original Article
- Keywords:
Herpes zoster;
Histamine test;
Prednisolone theraly
- MeSH:
Axons;
Heart;
Herpes Zoster*;
Histamine*;
Humans;
Incidence;
Kidney Transplantation;
Neuralgia;
Prednisolone;
Seasons;
Sensory Receptor Cells
- From:Korean Journal of Dermatology
1988;26(6):846-853
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We studied 283 patients with herpes zoster who visited to the Hangang Sacred Heart Hospital between January, 1982 and December, 1985 about the distribution of age, sex, seasonal incidence, associated diseases, camplications and the effect of systemic prednisolone on post herpetic neuralgia. And we also examined the functional states of involved sensory nerve endings by observing the axon flare response to histamine test. The results were as follows . 1. There was no significant differences in sexual and seasonal distributions. 2. There were low incidences of herpes zoster in age groups of below 20 years and over 70 years than age groups of 20 69 years. 3. Sites of involvement were thoracic(170 cases), cervical(38 cases), trigeminal(35 cases), lumbar(28 cases), sacral(11 cases) and facial(1 case) dermatomes. 4. Associated diseases were diabetes mellitus(7 cases), hypertension(7 cases). pulmonary tuberculosis(6 cases), malignant neoplasms(3 cases) and renal transplantation (1 case). 5. Complications were post herpetic neuralgia(18 cases), keratoconjunctivitis(9 cases), meningoencephalitis(1 case), Ramsay Hunt syndrome(1 case), urinary difficulty(1 case) and generalized varicelliform eruption(1 case). 6. The incidence of post-herpetic neuralgia was reduced by systemic prednisolone therapy in patients over 60 years. 7. There was no decrease of axon flare by histamine test on the affected area in 18 patients with herpes zoster.
