Dynamic Salivary Gland Scintigraphy in Clinical Sicca Syndrome: Comparison with Static images.
- Author:
Euy Neyng KIM
;
Hyung Sun SOHN
;
Jung Eun CHOI
;
Sung Hoon KIM
;
Yong An CHUNG
;
Soo Kyo CHUNG
;
Choon Yul KIM
- Publication Type:Original Article
- Keywords:
Salivary gland;
Radionuclide dynamic studies;
Tc-99m pertechnetate;
Clinical sicca syndrome
- MeSH:
Healthy Volunteers;
Humans;
Parotid Gland;
Radionuclide Imaging*;
Salivary Glands*;
Sjogren's Syndrome*;
Sodium Pertechnetate Tc 99m;
Submandibular Gland
- From:Korean Journal of Nuclear Medicine
2001;35(1):43-51
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: In this study, we compared the quantitative characteristics of dynamic salivary gland scintigraphy with static scintigraphy in patients with clinical sicca syndrome using Tc-99m pertechnetate. MATERIALS AND METHODS: Fifty-two parotid glands and 52 submandibular glands out of 26 patients with clinical sicca syndrome were studied by dynamic and static salivary gland scintigraphy. Ten normal volunteers were also studied as a control group for comparison of scintigraphic parameters. Ten minutes after injection of 370 MBq Tc-99m pertechnetate, we obtained pre-stimulus static images for a few minutes. Then dynamic salivary gland scintigraphy with lemon juice stimulation was performed for 20 minutes. Finally we obtained post-stimulus static images after dynamic images. On dynamic study, functional parameters such as uptake rate, secretion rate and re-uptake rate were calculated. The results of dynamic study and static images were compared. RESULTS: On dynamic study, we could obtain functional parameters of salivary glands successfully. On dynamic study, 22 parotid glands and 22 submandibular glands out of each of 52 glands are abnormal. The static images demonstrated somewhat different results, of which reasons we could assume via dynamic study. CONCLUSION: Dynamic salivary gland scintigraphy using Tc-99m perechnetate were more functional than static images and might be useful in the assessment of the functional change of the salivary gland in patients with clinical sicca syndrome.
