A case of Hashimoto's thyroiditis with chronic lymphocytic leukemia.
- Author:
Myong Su KANG
1
;
Sun Il LEE
;
Dong Woo KIM
;
Hee Jin KIM
;
Hyun Kyung CHUNG
;
Dong Su YOO
;
Jai Hyang GO
Author Information
1. Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea. hjinkim@dankook.ac.kr
- Publication Type:Case Report
- Keywords:
Autoimmune thyroiditis;
Chronic lymphocytic leukemia;
Autoimmune diseases
- MeSH:
Aged;
Antibodies;
Autoimmune Diseases;
Cyclophosphamide;
Drug Therapy;
Female;
Fibrosis;
Goiter;
Humans;
Leukemia, Lymphocytic, Chronic, B-Cell*;
Prednisolone;
Thyroglobulin;
Thyroid Diseases;
Thyroid Gland*;
Thyroiditis*;
Thyroiditis, Autoimmune
- From:Korean Journal of Medicine
2006;70(1):101-106
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hashimoto's thyroiditis is an autoimmune thyroid disease characterized by a gradual enlargement of the thyroid gland, extensive lymphocytic infiltration and fibrosis of thyroid follicles. Hashimoto's thyroiditis occurs frequently in conjunction with a wide range of organ-specific and systemic autoimmune diseases. The association of chronic lymphocytic leukemia with other autoimmune diseases also has been recognized. Here, we report a case of chronic lymphocytic leukemia diagnosed by abrupt painful swelling of the thyroid gland in a 69-year-old woman with Hashimoto's thyroiditis. The painful enlargement of goiter and elevated levels of antibodies to thyroglobulin were improved after chemotherapy with cyclophosphamide, vicristine and prednisolone.