Multiple Giant Keratoacanthoma Treated with Acitretin.
- Author:
Eun Sun KWON
1
;
Kyoung Geun LEE
;
Byoung Yong KOH
;
Ki Bum MYUNG
;
Seung Hyun CHEONG
Author Information
1. Department of Dermatology, Konyang University College of Medicine, Daejeon, Korea. mabie@kyuh.ac.kr
- Publication Type:Case Report
- Keywords:
Acitretin;
Giant keratoacanthoma;
Keratoacanthoma
- MeSH:
Acitretin*;
Biopsy;
Cytoplasm;
Ear;
Eosinophils;
Forearm;
Hand;
Humans;
Keratoacanthoma*;
Middle Aged
- From:Korean Journal of Dermatology
2017;55(4):249-252
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Giant keratoacanthoma is an uncommon variant of keratoacanthoma, which may increase to a diameter of several centimeters. Although keratoacanthomas usually resolve spontaneously, giant keratoacanthoma can be invasive and destructive. A 49-year-old man presented with a 5-year history of multiple large hyperkeratotic and crusted plaques and nodules on sun-exposed areas such as the face, ear, hand, and forearm. Some lesions involuted spontaneously, whereas others became rather enlarged. The biopsy specimen revealed horn-filled crater formation, epidermal extending resembling a buttress, and an eosinophilic glassy appearance in the keratinocytic cytoplasm. We treated the lesions with acitretin, and they almost completely resolved after 13 weeks. Here we describe a case of multiple giant keratoacanthoma treated with acitretin.
