Heart Retransplantation to Treat a Case of Refractory Cardiac Allograft Vasculopathy.
10.3904/kjm.2016.91.3.287
- Author:
Su Yeon LEE
1
;
Jin Oh CHOI
;
Yu Jin KIM
;
Jae Shin CHOI
;
Ga Yeon LEE
;
Jung Sun KIM
;
Eun Seok JEON
Author Information
1. Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Cardiac allograft vasculopathy;
Heart retransplantation
- MeSH:
Adolescent;
Allografts*;
Coronary Vessels;
Everolimus;
Heart Transplantation;
Heart*;
Humans;
Male;
Reperfusion
- From:Korean Journal of Medicine
2016;91(3):287-291
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cardiac allograft vasculopathy is one of the most important causes of poor long-term survival after heart transplantation. The condition tends to be diffuse, usually affecting the mid-to-distal portions of the coronary artery. Reperfusion therapy is ineffective. Everolimus, an inhibitor of proliferation signaling, has been reported to prevent development of the condition; however, the efficacy thereof has not yet been fully accepted. The only definitive treatment for cardiac allograft vasculopathy is retransplantation. Herein, we describe the case of a 15-year-old boy who underwent heart retransplantation because of rapidly progressive cardiac allograft vasculopathy.