Myelomatous Pleural Effusion with Elevated ADA Activity.
10.3904/kjm.2016.91.3.316
- Author:
Han Ju MOON
1
;
Dong Yeop SHIN
;
Hye Ryoun KIM
;
Yeon Won PARK
;
Seung Min WOO
;
Jin Hoon CHA
;
Kang Hee HAN
Author Information
1. Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Multiple myeloma;
Pleural effusion;
Tuberculosis;
Adenosine deaminase
- MeSH:
Adenosine Deaminase;
Bacillus;
Bone Marrow;
Drug Therapy;
Exudates and Transudates;
Humans;
Multiple Myeloma;
Neoplasms, Plasma Cell;
Pleural Effusion*;
Polymerase Chain Reaction;
Tuberculosis
- From:Korean Journal of Medicine
2016;91(3):316-320
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Multiple myeloma is a plasma cell neoplasm mainly involving the bone marrow and skeletal system. Myelomatous pleural effusion is rare, accounting for less than 1%. In cases with high adenosine deaminase (ADA) activity, with lymphocytic exudate in the pleural fluid, tuberculous pleural effusion should be differentiated first. We report herein a rare case of a unilateral pleural effusion in a patient who was undergoing chemotherapy for multiple myeloma, with an ADA level of > 100 IU/L and lymphocytic exudate in the pleural fluid. An acid fast bacillus stain and polymerase chain reaction test for tuberculosis were negative. Consequently, the patient was diagnosed with myelomatous pleural effusion with elevated ADA activity.
