A Case of Type V Hyperlipoproteinemia with Xanthoma Eruptivum.
- Author:
Sun Young LEE
1
;
Won Sin LEE
;
Sung Eun CHANG
;
Jee Ho CHOI
;
Kyung Jeh SUNG
;
Kee Chan MOON
;
Jai Kyoung KOH
Author Information
1. Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. derman@hanmir.com
- Publication Type:Case Report
- Keywords:
Type V hyperlipoproteinemia;
Xanthoma eruptivum
- MeSH:
Adolescent;
Biopsy;
Blood Glucose;
Buttocks;
Cholesterol;
Cicatrix;
Diabetes Mellitus;
Elbow;
Electrophoresis;
Extremities;
Female;
Gemfibrozil;
Humans;
Hyperlipoproteinemia Type V*;
Insulin;
Knee;
Lipoproteins;
Plasma;
Skin;
Triglycerides;
Xanthomatosis*
- From:Korean Journal of Dermatology
2001;39(8):935-937
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of type V hyperlipoproteinemia with xanthoma eruptivum associated with diabetes mellitus. An 18-year-old female patient presented with multiple, erythematous papules on the trunk, buttocks, and both extremities and multiple orange-yellow colored, conglomerated nodules on the elbows and knees. Laboratory examination showed increased serum blood glucose, cholesterol and triglyceride. Lipoprotein electrophoresis showed increased pre-beta and chylomicron bands. Analysis of lipoprotein revealed increase of very low density lipoprotein (VLDL) and triglyceride levels in the plasma. A skin biopsy from the papule on the trunk revealed a xanthoma. We diagnosed the patient as type V hyperlipoproteinemia. After 10 months of treatment with insulin and gemfibrozil, the serum levels of cholesterol and triglyceride were reduced to normal level. The skin lesions showed marked improvement without scar.
