Pulmonary Nocardiosis in a Patient with Lupus Nephritis.
- Author:
Sun Joo CHANG
1
;
Kang Nyoung LEE
;
Yoon Kyoung SUNG
;
Hye Soon LEE
;
Wan Sik UHM
;
Tae Hwan KIM
;
Jae Bum JUN
;
Hyun Joo PAI
;
Sang Cheol BAE
;
Seok Chol JEON
;
Dae Hyun YOO
Author Information
1. Division of Rheumatology, The Hospital for Rheumatic Diseases, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. dhyoo@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Lupus nephritis;
Nocardia;
Pulmonary Nocardiosis;
Acquired immune deficiency syndrome
- MeSH:
Acquired Immunodeficiency Syndrome;
Adrenal Cortex Hormones;
Bacterial Infections;
Connective Tissue Diseases;
Cyclophosphamide;
Humans;
Hyphae;
Lung Diseases;
Lupus Erythematosus, Systemic;
Lupus Nephritis*;
Nocardia;
Nocardia Infections*;
Nocardiaceae;
Opportunistic Infections;
Organ Transplantation;
Proteinuria;
Renal Insufficiency;
Risk Factors;
Transplants
- From:The Journal of the Korean Rheumatism Association
2005;12(1):47-51
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nocardiosis is uncommon in healthy people, but occurs as an opportunistic infection in patients with connective tissue disease, solid organ transplantation, lung disease, malignancies, and the acquired immune deficiency syndrome (AIDS). Nocardia is a gram positive, variably acid-fast aerobic bacterium of the family Nocardiaceae characterized by branching and filamentous growth, with distinctive aerial hyphae. In systemic lupus erythematosus (SLE) patients, immunosuppressiion with cytotoxic drugs or corticosteroids, proteinuria, renal insufficiency, and active SLE itself are known as risk factors for serious bacterial infections and opportunistic infections. We report a case of pulmonary Nocardiosis in patient with lupus nephritis treated with cyclophosphamide and high dose corticosteroid.
