A Case of Acute Renal Infarction with Protein S Deficiency.
- Author:
Su Ji KIM
1
;
Soon Oh HWANG
;
Moon Su KANG
;
Hyo Wook GIL
;
Jong Oh YANG
;
Eun Young LEE
;
Sae Yong HONG
Author Information
1. Department of Internal Medicine Soonchunhyang University, Cheonan Hospital, Cheonan, Korea. hwgil@schch.co.kr
- Publication Type:Case Report
- Keywords:
Infarction;
Protein S deficiency;
Thrombophilia
- MeSH:
Cardiovascular Diseases;
Humans;
Infarction;
Plasma;
Protein C;
Protein S;
Protein S Deficiency;
Thrombophilia;
Thrombosis;
Vitamin K
- From:Korean Journal of Nephrology
2008;27(3):393-396
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute renal infarction is an uncommon disease that is often misdiagnosed initially because of its nonspecific presentation. Cardiovascular disease is the major cause of thromboembolic event, but renal infarction can also occur in patient with special conditions such as hypercoagulable states. Protein S deficiency is a rare cause of the hypercoagulable states and induces both venous and arterial thrombosis. Protein S are a vitamin K dependent plasma protein that serves as a cofactor for the anticoagulant effects of activated protein C. Patients deficient in protein S is prone to recurrent thromboembolic disease. We reported a case of acute renal infarction that was associated with type II protein S deficiency in a 38-year old patient without underlying cardiovascular disease.
