Reproductive outcomes after laparoscopic radical trachelectomy for early-stage cervical cancer.
- Author:
Jeong Yeol PARK
1
;
Dae Yeon KIM
;
Dae Shik SUH
;
Jong Hyeok KIM
;
Yong Man KIM
;
Young Tak KIM
;
Joo Hyun NAM
Author Information
- Publication Type:Original Article
- Keywords: Cervical cancer; Fertility; Laparoscopic radical trachelectomy; Pregnancy outcome; Reproductive outcome
- MeSH: Abortion, Missed; Abortion, Spontaneous; Catheterization; Constriction, Pathologic; Dilatation; Dysmenorrhea; Female; Fertility; Follow-Up Studies; Humans; Interviews as Topic; Live Birth; Medical Records; Menstruation; Parturition; Pregnancy; Pregnancy Outcome; Pregnancy Rate; Premature Birth; Retrospective Studies; Uterine Cervical Neoplasms*
- From:Journal of Gynecologic Oncology 2014;25(1):9-13
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: The objective of this study was to estimate the reproductive outcome of young women with early-stage cervical cancer who underwent fertility-sparing laparoscopic radical trachelectomy (LRT). METHODS: We performed a retrospective review of the medical records of patients with early-stage cervical cancer who underwent LRT. Clinicopathological data were obtained from patient medical records, and reproductive outcome data were obtained from patient medical records and telephone interviews. RESULTS: Fifty-five patients who underwent successful LRT were included in this study. The median age of patients was 32 years (range, 22 to 40 years), and the median follow-up time after LRT was 37 months (range, 3 to 105 months). Menstruation resumed in all patients after LRT, with fifty patients (90.9%) and five patients (9.1%) reporting regular and irregular menstruation, respectively. Six patients (10.9%) presented with cervical stenosis, which was manifested by regular but decreased menstrual flow and newly-developed dysmenorrhea. These patients underwent cervical cannulation and dilatation. Eighteen patients (32.7%) attempted to conceive, with six out of 18 patients receiving fertility treatments. Fourteen pregnancies (i.e., four missed abortions, six preterm births and four full-term births) occurred in 10 patients after LRT. Nine out of 10 patients gave birth to 10 healthy babies. The pregnancy rate after LRT was 55.6% (10/18). The spontaneous abortion rate and live birth rate were 28.6% (4/14) and 71.4% (10/14), respectively. The preterm birth rate was 60% (6/10). CONCLUSION: Pregnancy and live birth rates after LRT were promising; however, the preterm birth rate was relatively high. Cervical stenosis also occurred in a small percentage of patients.
