The Effect of Aging on the Hemodynamic Response to Endotracheal Intubation during the Induction of Anesthesia.
10.4235/jkgs.2016.20.1.36
- Author:
Myoung Keun SHIN
1
;
Wang Gyu LEE
;
Haeng Seon SHIM
Author Information
1. Department of Anesthesiology and Pain Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea. 6512hs@naver.com
- Publication Type:Original Article
- Keywords:
Elderly;
Hemodynamic;
Intubation;
Sevoflurane
- MeSH:
Aged;
Aging*;
Anesthesia*;
Arterial Pressure;
Classification;
Heart Rate;
Hemodynamics*;
Humans;
Hypertension;
Intubation;
Intubation, Intratracheal*
- From:Journal of the Korean Geriatrics Society
2016;20(1):36-41
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The aim of this study was to evaluate the effect of aging on the hemodynamic response to endotracheal intubation during the induction of anesthesia. METHODS: Fifty patients with American Society of Anesthesiologists physical status classification 1 or 2 were enrolled and allocated according to age to either group N (35-44 years, not elderly, n=25) or group E (65-74 years, elderly, n=25). The patients were administered 3 minimum alveolar concentrations of sevoflurane for 5 minutes for the induction of anesthesia. Systolic arterial pressure (SAP) and heart rate (HR) were recorded before (baseline), immediately after (T0), and at 1-minute intervals during the first 4 minutes after endotracheal intubation (T1-T4). RESULTS: SAP increased by 15.4% and 10.8%(p<0.05) from the baseline at T0 and T1, respectively, in group N, and by 21.6%, 17.8%, and 11.8%(p<0.05) from the baseline at T0, T1 and T2 respectively, in group E. The SAP increases at T0, T1 and T2 were significantly greater in group E than in group N (p<0.05). The HR increases at T0 and T1 were significantly greater for group N than for group E (p<0.05). CONCLUSION: We recommend that anesthesiologists vigilantly monitor and attenuate adverse hemodynamic responses for at least 5 minutes after endotracheal intubation especially in elderly patients, particularly because significant systolic hypertension can occur in this age group.
