Plasma free amino acid profiles of canine mammary gland tumors.
10.4142/jvs.2012.13.4.433
- Author:
Kazuo AZUMA
1
;
Tomohiro OSAKI
;
Takeshi TSUKA
;
Tomohiro IMAGAWA
;
Saburo MINAMI
;
Yoshiharu OKAMOTO
Author Information
1. School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan. tosaki@muses.tottori-u.ac.jp
- Publication Type:Brief Communication
- Keywords:
dog;
mammary gland tumor;
plasma free amino acid
- MeSH:
Animals;
Aspartic Acid;
Dogs;
Mammary Glands, Human;
Neoplasm Metastasis;
Ornithine;
Plasma;
Risk Factors
- From:Journal of Veterinary Science
2012;13(4):433-436
- CountryRepublic of Korea
- Language:English
-
Abstract:
The purpose of this study was to elucidate the relationship between plasma free amino acid (PFAA) levels and the clinical stages of mammary gland tumors (MGT) in dogs. PFAA levels in canines with malignant mammary tumors were decreased compared to those of healthy animals. The levels of aspartate and ornithine, in the dogs with tumor metastasis were significantly decreased when compared to those of dogs that did not have metastases. Results of this study indicate that PFAA levels could be a risk factor or biomarker for canine MGT metastasis.