Hypothalamic-Pituitary-Gonadal Function in Hepatic Failure, Clinical Study.
- Author:
Young Kyoon KIM
1
;
Kwang Myung KIM
;
Sun Jin KIM
Author Information
1. Department of Urology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
hepatic failure;
hypothalamus;
pituitary;
gonad
- MeSH:
Ascites;
Erythema;
Esophageal and Gastric Varices;
Estradiol;
Follicle Stimulating Hormone;
Gonads;
Hemangioma;
Hepatic Insufficiency;
Hepatitis, Chronic;
Humans;
Hypothalamus;
Liver Cirrhosis;
Liver Failure*;
Luteinizing Hormone;
Male;
Plasma;
Spiders;
Testosterone
- From:Korean Journal of Urology
1988;29(4):538-542
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypothalamic-pituitary-gonadal function in male hepatic insufficiency was clinically in vestigated using cases of chronic hepatitis of viral origin, liver cirrhosis and non-hepatic control, with particular attention on incidencies of esophageal varix, spider angioma, palmar erythema and ascitic accumulation along with measurement of plasma levels of testosterone, estradiol, luteinizing hormone and follicle stimulating hormone. The following results were obtained : 1. Significant decreases of plasma testosterone and significant increase of estradiol were observed in cases of liver cirrhosis. The value of luteinizing hormone increased with significance. 2. Incidencies of esophageal varix, ascites, spider angioma and palmar erythema were higher in liver cirrhosis than in chronic hepatitis. 3. Decrease in testosterone level and increase of estradiol level were observed more prominently while there were higher grade of esophageal varix or presence of both spider angioma and palmar erythema throughout.
