The Clinical Utility of Positron Emission Tomography-computed Tomography in the Evaluation of Inflammatory Bowel Diseases.
- Author:
Sung Ho RYU
1
;
Jae Hee CHEON
;
Won Jun KANG
;
Jin Young KIM
;
Bo Kyung KIM
;
Jin Young YOON
;
Yoon Suk JUNG
;
Hyun Mi HEO
;
Jin Ha LEE
;
Soung Min JEON
;
Sung Pil HONG
;
Tae Il KIM
;
Won Ho KIM
Author Information
- Publication Type:Original Article
- Keywords: Inflammatory Bowel Disease; PET-CT; Clinical Utility
- MeSH: Colitis, Ulcerative; Colonoscopy; Electrons; Humans; Inflammatory Bowel Diseases; Male; Tuberculosis
- From:Intestinal Research 2011;9(2):97-104
- CountryRepublic of Korea
- Language:Korean
- Abstract: BACKGROUND/AIMS: Positron emission tomography-computed tomography (PET-CT) is a nuclear imaging technique that provides noninvasive, three dimensional, quantitative images. Recently, PET-CT has been shown to be valuable in assessing patients with inflammatory diseases; however, the clinical utility of PET-CT in the evaluation of inflammatory bowel disease (IBD) has not been defined. Thus, the aim of this study was to determine the clinical utility of PET-CT in the evaluation of IBD. METHODS: Between November 2006 and September 2010, clinical, endoscopic, and radiological data on 14 patients (6 males and 8 females: age range, 33-79 years) with suspected IBD were collected. The standard work-up method for a definite diagnosis of IBD included ileocolonoscopy. RESULTS: The 14 patients were divided into the following five groups: ulcerative colitis (n=4, 29%), intestinal Behcet's disease (n=3, 21%), intestinal tuberculosis (n=2, 14%), malignancy (n=2, 14%), and no abnormal findings with colonoscopy (n=3, 21%). A PET-CT based-diagnosis of IBD correlated with a colonoscopic diagnosis in nine cases (64.3%), but the matching ratio of the distribution of lesions between PET-CT findings and colonoscopic findings was only 18.1% (2/11). CONCLUSIONS: The utility of PET-CT in the diagnosis of IBD requires further evaluation.