A Clinical Study of the Effect of Periodontitis-Medical Gel on Human Gingivitis and Periodontitis.
10.5051/jkape.2000.30.1.11
- Author:
Jung Kiu CHAI
1
;
Jae Seong CHOI
;
Ji Sook PARK
;
Jong Gin SUH
;
Seong Ho CHOI
;
Kyoo Sung CHO
;
Chong Kwan KIM
Author Information
1. Department of Periodontology, College of Dentistry, Yonsei University Research Institute for Periodontal Regeneration, Korea.
- Publication Type:Original Article
- Keywords:
Dentheth(R);
periodontitis-medical gel;
Dipotassium glycyrrhizinate;
Allantoin;
Hinokitiol;
Cetylpyridinium chloride
- MeSH:
Allantoin;
Burns;
Calculi;
Cetylpyridinium;
Gingivitis*;
Glycyrrhizic Acid;
Hand;
Hemorrhage;
Humans*;
Nausea;
Periodontal Index;
Periodontitis*;
Surveys and Questionnaires;
Sensation;
Suppuration
- From:The Journal of the Korean Academy of Periodontology
2000;30(1):11-25
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study was to evaluate the clinical effects of Dipotassium glycyrrhizinate, Allantoin, Hinokitiol, Cetylpyridinium chloride containing gel(Dentheth(R)) on periodontitis. 41 patients with sites having pocket depth of 4-6mm were selected for the study. We classified 2 groups which consisted of 21 patients in the test group(exp.) and 20 patients in the control(placebo) respectively. Following a baseline examination, plaque and calculus were removed and then the experimental gel were handed out to the patients and topical application regimens were initiated. During the 4-week experimental period, pocket depth, bleeding on probing, gingival index, plaque index as a clinical parameters were measured in the baseline, 2 weeks, 4 weeks respectively. A questionnaire was delivered to each patients in 2 weeks, 4 weeks respectively. The results were as follows : 1.Probing pocket depth showed a significant difference in the Exp. group compared with the control group in the changes from baseline to 2 weeks(p<0.05), but there was no significant difference between the groups in the changes from baseline to 4 weeks, from 2 weeks to 4 weeks(p<0.05). 2.The Exp. group showed a significant difference compared with the control group in the changes from baseline to 2 weeks, from baseline to 4 weeks, from 2 weeks to 4 weeks in bleeding on probing(p<0.05). 3. The gingival index showed a significant difference compared with the control group in the changes from baseline to 2 weeks, from baseline to 4 weeks, from 2 weeks to 4 weeks after 4 weeks use of a gel(p<0.05). 4.The plaque index showed a significant difference in the Exp. group compared with the control group in the changes from baseline to 2 weeks(p<0.05), but there was no significant difference between the groups in the changes from baseline to 4 weeks, from 2 weeks to 4 weeks(p<0.05). 5.A questionnaire was consisted of 5 kinds as to bleeding, pus discharge, pain, burning sensation, patient's satisfaction and all of the questions showed a significant difference compared with the control group in the changes from 2 weeks to 4 weeks(p<0.05). 6.During the 4-week experimental period, important side-effects were not finded out, but each groups had one patient appealed nausea or discomfort respectively. These results indicate that application of periodontitis-medical gel was useful as an additional aid of mechanical treatment.
