Evaluating the effect of two antibiotic regimens for purulent meningitis in infants at the Pediatric Institute
- Author:
An Nhat Pham
- Publication Type:Journal Article
- Keywords:
purulent meningitis
- MeSH:
Meningitis;
Infant
- From:Journal of Practical Medicine
2002;435(11):9-11
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Participants in this study were 153 pediatric patients aged 1 - 12 months who admitted the Pediatric Institute with diagnosis of purulent meningitis between January 1994 and June 1998. These patients were divided into 2 groups. 89 infants were involved in group 1, and 64 were involved in group 2. The results showed that the antibiotic regimen using Claforan with dose of 150-200 mg/kg/24h was superior to the regimen using ampicilline plus chloramphenicol for purulent meningitis in infants, especially for infants who had a delay in seeking health care. Generation 3 of cephalosporine (ceftriasone) has high sensitivity to H. influenzae and rate of resistance to this antibiotic was lower significantly than that of ampicilline and chloramphenicol.
