Pulsed Intravenous Immunoglobulin Therapy in Livedo Vasculitis: Report of Two Cases.
- Author:
Hee Jin BYUN
1
;
Hyun Sun PARK
;
Seong Uk MIN
;
Hyo Seung SHIN
;
Kapsok LI
;
Chong Hyun WON
;
Soyun CHO
Author Information
1. Department of Dermatology, Seoul National University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
Intravenous immunoglobulin;
Livedo vasculitis
- MeSH:
Immunization, Passive*;
Immunoglobulins*;
Korea;
Lower Extremity;
Skin Diseases;
Steroids;
Thrombolytic Therapy;
Ulcer;
Vasculitis*
- From:Korean Journal of Dermatology
2006;44(10):1231-1234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Livedo vasculitis is a chronic dermatosis characterized by recurrent painful ulceration of the lower limbs, which heals to leave atrophie blanche. The precise pathophysiology is not known. Antiplatelet, anticoagulant, fibrinolytic therapies and anabolic steroids have been reported to be helpful in this syndrome. However, no consistent benefit has been demonstrated with any treatment modality. Recently, pulsed intravenous immunoglobulin therapy has been reported to be effective in some refractory cases. We herein report two cases of recalcitrant livedo vasculitis which were effectively treated with pulsed intravenous immunoglobulin therapy. These were the first trials carried out in Korea.