Pharmacological Therapy in Osteoarthritis.
10.5124/jkma.2003.46.11.958
- Author:
Yeong Wook SONG
1
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine & Hospital, Korea. ysong@sun.ac.kr
- Publication Type:Original Article
- Keywords:
Osteoarthritis;
Acetaminophen;
Nonsteroidal anti-inflammatory drug;
Disease modifying osteoarthritis drug
- MeSH:
Acetaminophen;
Capsaicin;
Cartilage;
Chondroitin Sulfates;
Glucosamine;
Osteoarthritis*;
Steroids;
Viscosupplements
- From:Journal of the Korean Medical Association
2003;46(11):958-964
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Osteoarthdtis (OA) is a common, chronic, and painful disorder characterized by cartilage loss. It is the most common among all rheumatic disorders and is a major cause of disability. OA can be managed with a variety of pharmacological therapies, including acetaminophen, traditional nonsteroidal antiinflammatory drugs, cyclooxygenase2 inhibitors, intraarticular steroids, viscosupplements, glucosamine, chondroitin sulfate, and capsaicin. In this review, I describe the clinical efficacy and side effects of these pharmaceuticals and review diseasemodifying osteoarthritis drugs (DMOAD), such as glucosamine, diacerein, and avocado/soybean unsaponifiables, of which the clinical efficacy still remains to be determined.
