Completeness of pedigree and family cancer history for ovarian cancer patients.
10.3802/jgo.2014.25.4.342
- Author:
Yedong SON
1
;
Myong Cheol LIM
;
Sang Soo SEO
;
Sokbom KANG
;
Sang Yoon PARK
Author Information
1. Center for Uterine Cancer, National Cancer Center, Goyang, Korea. parksang@ncc.re.kr, gynlim@gmail.com
- Publication Type:Original Article
- Keywords:
Completeness;
Family history;
Lynch syndrome;
Ovarian cancer;
Pedigree
- MeSH:
Adult;
Age Distribution;
Age of Onset;
Aged;
Colorectal Neoplasms, Hereditary Nonpolyposis/genetics;
Cross-Sectional Studies;
Female;
Genetic Predisposition to Disease;
Humans;
Medical History Taking/*methods;
Middle Aged;
Neoplasm Staging;
Ovarian Neoplasms/*genetics/pathology;
Pedigree;
Young Adult
- From:Journal of Gynecologic Oncology
2014;25(4):342-348
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To investigate the completeness of pedigree and of number of pedigree analysis to know the acceptable familial history in Korean women with ovarian cancer. METHODS: Interview was conducted in 50 ovarian cancer patients for obtaining familial history three times over the 6 weeks. The completeness of pedigree is estimated in terms of familial history of disease (cancer), health status (health living, disease and death), and onset age of disease and death. RESULTS: The completion of pedigree was 79.3, 85.1, and 85.6% at the 1st, 2nd, and 3rd time of interview and the time for pedigree analysis was 34.3, 10.8, and 3.1 minutes, respectively. The factors limiting pedigree analysis were as follows: out of contact with their relatives (38%), no living ancestors who know the family history (34%), dispersed family member because of the Korean War (16%), unknown cause of death (12%), reluctance to ask medical history of relatives (10%), and concealing their ovarian cancer (10%). The percentage of cancers revealed in 1st (2%) and 2nd degree (8%) relatives were increasing through surveys, especially colorectal cancer related with Lynch syndrome (4%). CONCLUSION: Analysis of pedigree at least two times is acceptable in Korean woman with ovarian cancer from the first study. The completion of pedigree is increasing, while time to take family history is decreasing during three time survey.
