Treatment of Patients with Refractory Atopic Dermatitis Sensitized to House Dust Mites by Using Sublingual Allergen Immunotherapy.
- Author:
Joon Seok CHOI
1
;
Ha Ryeong RYU
;
Cheol Hyun YOON
;
Ji Hoon KIM
;
Jin Ok BAEK
;
Joo Young ROH
;
Jong Rok LEE
Author Information
- Publication Type:Case Report
- Keywords: Atopic dermatitis; Pyroglyphidae; Sublingual immunotherapy
- MeSH: Dermatitis, Atopic*; Desensitization, Immunologic*; Humans; Immunotherapy; Pyroglyphidae*; Skin Diseases; Sublingual Immunotherapy
- From:Annals of Dermatology 2015;27(1):82-86
- CountryRepublic of Korea
- Language:English
- Abstract: Even though atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases, its treatment remains a challenge in clinical practice, with most approaches limited to symptomatic, unspecific anti-inflammatory, or immunosuppressive treatments. Many studies have shown AD to have multiple causes that activate complex immunological and inflammatory pathways. However, aeroallergens, and especially the house dust mite (HDM), play a relevant role in the elicitation or exacerbation of eczematous lesions in many AD patients. Accordingly, allergen-specific immunotherapy has been used in AD patients with the aim of redirecting inappropriate immune responses. Here, we report three cases of refractory AD sensitized to HDM who were treated with sublingual immunotherapy.
