A Case of Systemic Inflammatory Response Syndrome Secondary to an Acute Polyarticular Gout.
10.4235/jkgs.2012.16.3.158
- Author:
Ji Hyun CHEON
1
;
Ji Ung KIM
;
Sun Kwang KIM
;
Sung Hyun KO
;
Jun Ho JO
;
Geon Woo PARK
;
Jin Suk LEE
;
Hyoung Yoel PARK
Author Information
1. Department of Internal Medicine, Busan Veterans Hospital, Busan, Korea. drcecil@hanmail.net
- Publication Type:Case Report
- Keywords:
Gout;
Systemic inflammatory response syndrome;
Sepsis
- MeSH:
Arthritis;
Arthritis, Gouty;
Arthritis, Infectious;
Diagnosis, Differential;
Gout;
Inflammation;
Joints;
Sepsis;
Systemic Inflammatory Response Syndrome;
Uric Acid
- From:Journal of the Korean Geriatrics Society
2012;16(3):158-161
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gout occurs as a response to monosodium urate crystal, that is present in joints, bones and soft tissue. The classic symptoms of gouty arthritis are recurrent attacks of acute, markedly painful monoarticular or oligoarticular inflammation; but polyarthritis and chronic arthritis can also occur. Differential diagnosis from infectious arthritis is important. A definitive diagnosis requires the direct identification of urate crystals in the joint, and the exclusion of infection. We report the case of systemic inflammatory response syndrome (SIRS), developed from acute polyarticular gout. SIRS is characterized by loss of local control of inflammation, or an overly activated response resulting in an exaggerated systemic response. The SIRS was presumably due to systemic effects of a localized inflammatory response to urate crystals.
