Relapsed Wilms' tumor with multiple brain metastasis.
10.3345/kjp.2016.59.11.S96
- Author:
Akın AKAKIN
1
;
Baran YILMAZ
;
Murat Sakir EKŞI
;
Ozlem YAPICIER
;
Türker KILIÇ
Author Information
1. Department of Neurosurgery, Bahçeşehir University Medical Faculty, Istanbul, Turkey.
- Publication Type:Case Report
- Keywords:
Wilms tumor;
Metastasis;
Surgery;
Radiotherapy;
Chemotherapy
- MeSH:
Brain*;
Cerebellum;
Child;
Diagnosis;
Drug Therapy;
Female;
Glycogen Storage Disease Type VI;
Humans;
Neoplasm Metastasis*;
Radiotherapy;
Seizures;
Wilms Tumor*
- From:Korean Journal of Pediatrics
2016;59(Suppl 1):S96-S98
- CountryRepublic of Korea
- Language:English
-
Abstract:
Wilms' tumor is the most common malignant renal tumor in childhood. The brain metastasis of a Wilms' tumor with anaplastic histopathology is rare. We present the case of an 8-year-old girl with Wilms' tumor, who presented with multiple brain metastases 5 years after her primary diagnosis. The brain masses were diagnosed after a generalized tonic-clonic seizure attack. The big solid mass in the cerebellum was resected, and whole-brain radiotherapy was performed, after which, she succumbed to her disease. In the case of clinical suspicion, cranial surveillance should be included in the routine clinical work-up for Wilms' tumor. Combined aggressive therapy (surgery+radiotherapy+chemotherapy) should be applied whenever possible, for both better survival and palliative aspects.
