Neurosyphilis Presenting with Multiple Cranial Neuropathy.
- Author:
On Hwa RYU
1
;
Han A KIM
;
Ju Kyung LEE
;
Shin Kwang KANG
;
Seong Han KIM
;
Joong Koo KANG
Author Information
1. Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. jkkang@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Neurosyphilis;
Multiple cranial neuropathy
- MeSH:
Adult;
Biopsy;
Brain;
Cranial Nerve Diseases*;
Fluorescent Treponemal Antibody-Absorption Test;
Hearing Loss;
Humans;
Inflammation;
Magnetic Resonance Imaging;
Necrosis;
Neurosyphilis*;
Penicillins;
Sexually Transmitted Diseases;
Tuberculosis
- From:Journal of the Korean Neurological Association
2015;33(1):36-39
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neurosyphilis can present with various clinical symptoms. We report a patient with multiple cranial neuropathy that, mimicked tuberculosis, but was finally diagnosed as neurosyphilis. A 38-year-old man was admitted due to subacutely progressive hearing loss. Brain MRI revealed multiple dural enhanced masses on contrast-enhanced T1 weighted images. Brain biopsy of the dural enhanced lesion revealed chronic granulomatous inflammation with coagulation necrosis, compatible with syphilitic gumma. Serum venereal disease research laboratory and fluorescent treponemal antibody absorption test results were positive. Treatment with penicillin resolved the patient's symptom.
