A Case with the Syndrome of Inappropriate Antidiuretic Hormone Associated with Sertraline.
- Author:
Sang Hyuk LEE
1
;
Sung Kil MIN
Author Information
1. Department of Psychiatry, College of Medicine, Yonsei University, Seoul, Korea. skmin518@yunc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Sertraline;
The syndrome of inappropriate antidiuretic hormone(SIADH);
Hyponatremia
- MeSH:
Aged;
Anorexia;
Diagnosis;
Eating;
Humans;
Hyponatremia;
Inappropriate ADH Syndrome;
Male;
Nausea;
Osmolar Concentration;
Sertraline*
- From:Korean Journal of Psychopharmacology
1999;10(1):95-98
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Authors report a case of syndrome of inappropriate antidiuretic hormone(SIADH) associated with sertraline. A 77 years-old male patient showed decreased serum & urine osmolality with symptoms of nausea and anorexia after the ingestion of sertraline, 50 mg for four days, which led to the diagnosis of SIADH. The symptoms of nausea and anorexia improved as serum osmolality improved in several days after discontinuation of sertraline. It is recommended to check serum Na level routinely at the initial treatment when patients on SRRI aggrevate in symptom, have a past history of hyponatremia, or are old.