A Case of More Abundant and Dysplastic Adenomas in the Interposed Colon than in the Native Colon.
10.3349/ymj.2007.48.6.1075
- Author:
Hye Jin HWANG
1
;
Kyung Ho SONG
;
Young Hoon YOUN
;
Ji Eun KWON
;
Hoguen KIM
;
Jae Bock CHUNG
;
Yong Chan LEE
Author Information
1. Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea. leeyc@yuhs.ac
- Publication Type:Case Report
- Keywords:
Esophageal colon interposition;
adenocarcinoma
- MeSH:
Adenocarcinoma/pathology;
Adenoma/etiology/*pathology;
Colon/*pathology;
Colonic Neoplasms/etiology/*pathology;
Disease Progression;
Esophagoplasty/adverse effects/methods;
Female;
Humans;
Middle Aged;
Postoperative Complications/etiology/pathology;
Time Factors
- From:Yonsei Medical Journal
2007;48(6):1075-1078
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a 60-year-old woman with intramucosal adenocarcinoma arising in the interposed colon, 40 years after the esophageal reconstruction for lye induced esophageal stricture. Although synchronous adenomas were also found in the native colon where the graft was taken, the number of adenomas was greater in the interposed colon and more dysplastic, even progressed to adenocarcinoma, than that of the native colon. The microsatellite instability-testing performed in the intramucosal carcinoma from interposed colon showed absence of microsatellite instability. Changing of location and functional deman]d of colonic segment, and the exposure to different intraluminal contents might have facilitated the adenoma- carcinoma transformation in the interposed colon.
