Accidental Intrathecal Vincristine Administration.
- Author:
Hye Mi RHOU
1
;
Kyung Duk PARK
Author Information
1. Department of Pediatrics, Chungnam National University College of Medicine, Korea. kdpark@cnuh.co.kr
- Publication Type:Case Report
- Keywords:
Vincristine;
Intrathecal therapy;
Ascending myeloencephalopathy
- MeSH:
Child;
Coma;
Humans;
Male;
Meningoencephalitis;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Vincristine*
- From:Korean Journal of Pediatric Hematology-Oncology
1999;6(2):347-351
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Accidental intrathecal vincristine instillation is a fatal error. We report a case of a 6-year-old boy with acute lymphocytic leukemia who suffered an accidental intrathecal vincristine administration. He suffered a progressive ascending chemical meningoencephalitis followed by coma, and died at the 5th day after injection. Several previous reports of intrathecal vincristine instillation are reviewed.
