A case of primary small cell neuroendocrine carcinoma of the liver.
- Author:
June Young YOON
1
;
Hyoung Jung CHUNG
;
Hyeyoung CHOI
;
Jong Su CHOI
;
Dae Woon EOM
;
Ho Suk OH
Author Information
1. Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea. hosukoh@hanmail.net
- Publication Type:Case Report
- Keywords:
Liver;
Small cell carcinoma;
Chemotherapy
- MeSH:
Aged;
Biopsy;
Carcinoma, Neuroendocrine;
Carcinoma, Small Cell;
Drug Therapy, Combination;
Female;
Follow-Up Studies;
Humans;
Incidence;
Liver;
Neuroendocrine Tumors;
United States
- From:Korean Journal of Medicine
2010;79(1):67-71
- CountryRepublic of Korea
- Language:English
-
Abstract:
Extrapulmonary small cell carcinoma is a highly malignant and poorly differentiated neuroendocrine tumor. The overall incidence in the United States is approximately 0.1~0.4%. Moreover, small cell carcinoma of the liver is extremely rare and few cases have been reported in the literature. We experienced a 65-year-old woman with a 15 cm hepatic mass, which was localized in the left lobe of a noncirrhotic liver. The mass was confirmed as small cell carcinoma by immunohistochemical staining of a biopsy specimen. Other possible primary sites were excluded by radiologic and endoscopic evaluations. The patient was treated with combination chemotherapy. She was in partial response on the last follow-up visit.