Two Cases of Keratosis Palmaris et Plantaris.
- Author:
You Ho CHAE
;
Sung Hwa KIM
;
Sang Won KIM
- Publication Type:Case Report
- Keywords:
Keratosis palmaris et plantaris;
Thost - Unna type;
Vitamin A treatment
- MeSH:
Adult;
Biopsy;
Family Characteristics;
Humans;
Hyperhidrosis;
Hyperplasia;
Keratoderma, Palmoplantar*;
Keratosis*;
Male
- From:Korean Journal of Dermatology
1985;23(2):229-234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We described here-in a 36-year-old male patient (case 1) with a severe form of keratosis palmaris et plantaris(Thost-Unna type) which was diffuse hyperkeratosis with hyperhidrosis on the entire surface of the palms and soles. His son, 8-year- old boy, showed symmetrical distribution of hyperkeratotic patches on the inner sides of both great toes(case 2). Therefore, it was suggested this genodermatosis occured in two generations of a family. The biopsy taken from the right palm of case 1 showed features of epidermal hyperplasia with hyperkeratosis, hypergranulosis and acanthosis. We tried the oral Vit. A therapy(50,000 unit, daily) in case 2. The hyperkeratotic lesions became slightly improved in 4 months after therapy.
