A Case of a Patient with Both Chorea and Restless Legs Syndrome.
10.3346/jkms.2008.23.3.533
- Author:
Yoon Kyung SHIN
1
;
Seung Chul HONG
;
Yon Kwon IHN
;
Jong Hyun JEONG
;
Jin Hee HAN
;
Sung Pil LEE
Author Information
1. Department of Psychiatry, St. Vincent's Hospital, The Catholic University of Korea College of Medicine, Suwon, Korea. hscjohn@hotmail.com
- Publication Type:Case Report
- Keywords:
Restless Legs Syndrome;
Chorea;
Sleep Initiation and Maintenance Disorde;
Depression;
Tramadol
- MeSH:
Adult;
Analgesics, Opioid/therapeutic use;
Anti-Dyskinesia Agents/therapeutic use;
Chorea/*complications/pathology;
Citalopram/therapeutic use;
Drug Therapy, Combination;
Haloperidol/therapeutic use;
Humans;
Kidney Failure, Chronic/*complications;
Magnetic Resonance Imaging;
Male;
Restless Legs Syndrome/*complications/drug therapy/pathology;
Serotonin Uptake Inhibitors/therapeutic use;
Tramadol/therapeutic use
- From:Journal of Korean Medical Science
2008;23(3):533-536
- CountryRepublic of Korea
- Language:English
-
Abstract:
The patient was a 44-yr-old man with end-stage renal disease who had developed chorea as a result of hypoglycemic injury to the basal ganglia and thalamus and who was subsequently diagnosed with depression and restless legs syndrome (RLS). For proper management, the presence of a complex medical condition including two contrasting diseases, chorea and RLS, had to be considered. Tramadol improved the pain and dysesthetic restlessness in his feet and legs, and this was gradually followed by improvements in his depressed mood, insomnia, lethargy, and feelings of hopelessness. This case suggests that the dopaminergic system participates intricately with the opioid, serotoninergic, and noradrenergic systems in the pathophysiology of RLS and pain and indirectly of depression and insomnia.
