Endobronchial ALK-Positive Anaplastic Large Cell Lymphoma Presenting Massive Hemoptysis.
10.4046/trd.2015.78.4.390
- Author:
Hee Kyung KIM
1
;
Bo Hye KIM
;
Sae Ahm KIM
;
Jae Kyoung SHIN
;
Ji Hyun SONG
;
Ah Young KWON
;
Jung Hyun KIM
;
Eun Kyung KIM
;
Ji Hyun LEE
;
Gwaung Il KIM
;
Hye Cheol JEONG
Author Information
1. Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. jhcmd@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Large Cell Lymphoma;
Respiratory Failure;
Hemoptysis
- MeSH:
Abdominal Pain;
Aged;
Biopsy;
Diagnosis;
Dyspnea;
Emergencies;
Emergency Service, Hospital;
Female;
Hemoptysis*;
Humans;
Lost to Follow-Up;
Lung;
Lung Neoplasms;
Lymph Nodes;
Lymphoma;
Lymphoma, Large-Cell, Anaplastic*;
Radiotherapy;
Respiratory Insufficiency;
Thorax
- From:Tuberculosis and Respiratory Diseases
2015;78(4):390-395
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary anaplastic large cell lymphoma (ALCL) of the lung is highly aggressive and quite rare. We report here a case of anaplastic lymphoma kinase-positive endobronchial ALCL, that was initially thought to be primary lung cancer. A 68-year-old woman presented with hemoptysis, dyspnea, and upper respiratory symptoms persisting since 1 month. The hemoptysis and and bronchial obstruction lead to respiratory failure, prompting emergency radiotherapy and steroid treatment based on the probable diagnosis of lung cancer, although a biopsy did not confirm malignancy. Following treatment, her symptoms resolved completely. Chest computed tomography scan performed 8 months later showed increased and enlarged intra-abdominal lymph nodes, suggesting lymphoma. At that time, a lymph node biopsy was recommended, but the patient refused and was lost to follow up. Sixteen months later, the patient revisited the emergency department, complaining of persistent abdominal pain since several months. A laparoscopic intra-abdominal lymph node biopsy confirmed a diagnosis of ALCL.
