Factors Influencing the Pathogenicity of Entamoeba Histolytica.
- Author:
Chin Thack SOH
1
Author Information
- Publication Type:Review
- MeSH: 2-Acetylaminofluorene; Animal; Antigens, Neoplasm/*isolation and purification; Antigens, Surface/isolation and purification; Diethylnitrosamine; Liver Neoplasms, Experimental/chemically induced/*immunology; Methyldimethylaminoazobenzene; Rats; Rats, Inbred Strains; Support, Non-U.S. Gov't
- From:Yonsei Medical Journal 1988;29(1):1-10
- CountryRepublic of Korea
- Language:English
- Abstract: In summarizing the results of the experimental studies up to the present, it is conjectured that the pathogenicity of Entamoeba histolytica or establishment of amoebiasis is not unique but differs by strain and age of Entamoeba histolytica and the age of the host. A non-virulent strain is more likely adapt to as low a temperature as 32 . This is not so in the strains which originated form clinical cases. Iso-enzyme patterns may roughly characterize pathogenic strains from non-pathogenic, Red blood cells may contribute as nutrients for growth of Entamoeba histolytica only after they have been hemolysed, but they are toxic to the amoebae as long as they remains intact. A low protein diet and stress may facilitate the establishment of amoebiasis; male sex hormones or previous infection by enteric bacteria provide a more advantageous condition than the female; and hepatotoxic agents will accelerate amoebic hepatitis.
