A Case of Renal Hypouricemia and Hypercalciuria.
- Author:
Gi Hyeon SEO
1
;
Sang Su BAE
;
Sang Joon PARK
;
Hye Young KIM
;
Woo Seong HUH
;
Yoon Ha LEE
;
Yoon Goo KIM
;
Ha Young OH
Author Information
1. Division of Nephrology, Department of Medicine Samsung Medical Center, Sung Kyun Kwan University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Hypouricemia;
Renal tubule;
Hypercalciuria;
Pyrazinamide;
Probenecid
- MeSH:
Acute Kidney Injury;
Adult;
Calcium;
Diet;
Humans;
Hypercalciuria*;
Probenecid;
Pyrazinamide;
Uric Acid;
Urolithiasis
- From:Korean Journal of Nephrology
1998;17(1):128-133
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We encountered a case of renal hypouricemia and absorptive hypercalciuria. Although renal hypouricemia is asymptomatic as usual, it is rarely complicated with acute renal failure and urolithiasis. A 43-year-old man had hypouricemia (serum uric acid, 0.6-1.0mg/dl) with an increased renal uric acid clearance (69.4ml/min), hypercalciuria (367.2mg/day). In present case, there was no response of uric acid excretion to either pyrazinamide or probenecid and hypercalciuria disappeared after calcium restriction diet. These results suggest that the present case had the defect of both pre-and postsecretory reabsorption of uric acid and absorptive hypercalciuria.
