Antimicrobial susceptibility and molecular detection of chloramphenicol and florfenicol resistance among Escherichia coli isolates from diseased chickens.
- Author:
Xin Sheng LI
1
;
Gui Qin WANG
;
Xiang Dang DU
;
Bao An CUI
;
Su Mei ZHANG
;
Jian Zhong SHEN
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords: antimicrobial resistance; Escherichia coli; flo-rfenicol
- MeSH: Animals; Anti-Bacterial Agents/*pharmacology; *Chickens; China/epidemiology; Chloramphenicol/pharmacology; DNA, Bacterial/chemistry/genetics; Drug Resistance, Multiple, Bacterial; Escherichia coli/*drug effects/growth & development; Escherichia coli Infections/epidemiology/microbiology/*veterinary; Microbial Sensitivity Tests/veterinary; Polymerase Chain Reaction/veterinary; Poultry Diseases/epidemiology/*microbiology; Thiamphenicol/analogs & derivatives/pharmacology
- From:Journal of Veterinary Science 2007;8(3):243-247
- CountryRepublic of Korea
- Language:English
- Abstract: Seventy Escherichia coli isolates recovered from diseasedchickens diagnosed with colibacillosis in Henan Province,China, between 2004 and 2005 were characterized forantimicrobial susceptibility profiles via a broth doublingdilution method. Overall, the isolates displayed resistanceto trimethoprim-sulfamethoxazole (100%), oxytetracycline(100%), ampicillin (83%), enrofloxacin (83%), and ciprofloxacin(81%), respectively. Among the phenicols, resistance wasapproximately 79% and 29% for chloramphenicol andflorfenicol, respectively. Molecular detection revealed thatthe incidence rates of the floR, cmlA, cat1, cat2 and cat3were 29, 31, 16, 13, and 0%, respectively. Additionally,10% of the isolates were positive for both floR and cmlA.As these antimicrobial agents may potentially inducecross-resistance between animal and human bacterialpathogens, their prudent use in veterinary medicine ishighly recommended.
