- Author:
Ji Yeon LEE
1
;
Helen Ki SHINN
;
Tae Jung KIM
;
Young Deog CHA
;
Ha Na SONG
;
Chun Woo YANG
Author Information
- Publication Type:Case Report
- Keywords: cancer; epidural morphine; ketamine
- MeSH: Analgesia, Epidural*; Humans; Ketamine; Lung Neoplasms*; Lung*; Male; Middle Aged; Morphine*; Neck Pain; Neoplasm Metastasis
- From:The Korean Journal of Pain 2006;19(1):96-100
- CountryRepublic of Korea
- Language:Korean
- Abstract: Pain control is very important in managing terminal cancer patients and there are several modalities to alleviate their pain. A high dosage of epidural morphine is effective to control terminal cancer pain. Furthermore, to decrease the amount of morphine, adding an alternative adjuvant like ketamine to the morphine regimen is considered helpful for controlling the pain of a terminal cancer patient. A 45 year old male patient with terminal lung cancer had neck pain that was caused by multiple bone metastases. Continuous epidural block was started with 2 mg/day of morphine and the dosage was gradually increased to 90 mg/day in 86 days. 30 mg/day of ketamine was then added to it. Overall, the morphine and ketamine dosages were increased to 564 mg/day and 140 mg/day, respectively, in 11 months until the patient expired. In this case, the high dosage of epidural morphine, 580 mg/day, was administered to control cancer pain without any severe adverse effects.