A Case of Pseudo-Meigs' Syndrome Associated with Ovarian Metastases from Breast Cancer.
10.4048/jbc.2012.15.4.474
- Author:
Koma NAITO
1
;
Shoji OURA
;
Hironao YASUOKA
;
Yoshitaka OKAMURA
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University School of Medicine, Wakayama, Japan. soura@wakayama-med.ac.jp
- Publication Type:Case Report
- Keywords:
Breast neoplasms;
Ovarian metastasis;
Ovariectomy;
Pseudo-Meigs' syndrome
- MeSH:
Aromatase;
Ascites;
Breast;
Breast Neoplasms;
Drainage;
Estrogens;
Female;
Humans;
Lymph Node Excision;
Mastectomy, Segmental;
Neoplasm Metastasis;
Ovariectomy;
Picibanil;
Pleural Effusion;
Positron-Emission Tomography;
Recurrence
- From:Journal of Breast Cancer
2012;15(4):474-477
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 54-year-old woman with long-lasting pleural effusion developed abdominal distention due to ascites from bilateral ovarian tumors. The patient had undergone breast-conserving surgery and axillary lymph node dissection for left breast cancer in October 2000, and had developed left pleural effusion in July 2006. Cytological examination of the pleural effusion found no malignant cells. Thoracic drainage with intrathoracic administration of OK-432 (Picibanil) had failed to control the pleural effusion. Positron emission tomography taken at the abdominal distention showed bilateral ovarian tumors. After failure to control the ascites with systemic and intra-abdominal chemotherapy, bilateral oophorectomy resulted in normalization of elevated serum tumor-marker levels and the disappearance of both the ascites and pleural effusions (i.e., pseudo-Meigs' syndrome). Pathological examination showed the tumors to be estrogen receptor-positive metastatic ovarian tumors from her breast cancer. The patient remained well with no further recurrence for 40 months under aromatase inhibitor therapy.