A Case of Silent Corticotroph-cell Adenoma with Elevated Serum ACTH.
- Author:
Jeong Geun MOON
1
;
So Young PARK
;
Byoung Chul CHO
;
Jung Min LEE
;
Si Hoon LEE
;
Yoo Mee KIM
;
Yu Mie RHEE
;
Bong Soo CHA
;
Hyun Chul LEE
;
Sung Kil LIM
Author Information
1. Department of Internal Medicine Yonsei University College of Medicine, National Health Insurance Corporation Ilsan Hospital1, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Pituitary adenoma;
ACTH;
SCCA
- MeSH:
Adenoma*;
Adrenocorticotropic Hormone*;
Brain;
Cushing Syndrome;
Headache;
Humans;
Hydrocortisone;
Magnetic Resonance Imaging;
Middle Aged;
Pituitary Neoplasms
- From:Journal of Korean Society of Endocrinology
2004;19(5):535-541
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 48 year-old man was referred to our Department with a headache, and also presented with an elevated serum ACTH level, but without an elevated serum cortisol. Although there was no clinical evidence of Cushing's syndrome, a brain CT and MRI showed a 4x4.5 cm sized pituitary mass, which was successfully removed by a transsphenoidal approach (TSA). A histopathological examination revealed the mass to have an ACTH positive reaction. Therefore, through hormonal and pathological evaluation, a silent corticotroph-cell adenoma (SCCA), with an elevated serum ACTH level, was diagnosed. Although reports on SCCA have been recently increased, this case is reported because these kinds of tumor are still rare, and those SCCA with an elevated serum ACTH even more so
