A Case of Adrenal Insufficiency Associated with Antiphopholipid Syndrome with SLE.
- Author:
Sun Hye SHIN
1
;
Jung Hee KIM
;
Jung Min SON
;
Jeong Su KIM
;
Min Ah NA
;
Yang Ho KANG
;
Ok Nyu KONG
;
Seok Dong YOO
;
Seok Man SON
;
In Ju KIM
;
Yong Ki KIM
Author Information
1. Department of Internal Medicine, School of Medicine, Pusan National University, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Antiphopholipid syndrome;
Adrenal hemorrhage
- MeSH:
Abdominal Pain;
Adrenal Glands;
Adrenal Insufficiency*;
Antibodies, Anticardiolipin;
Autoimmune Diseases;
Glucocorticoids;
Hemorrhage;
Humans;
Lupus Coagulation Inhibitor;
Lupus Erythematosus, Systemic;
Magnetic Resonance Imaging;
Nausea;
Necrosis;
Thrombosis;
Veins;
Vomiting
- From:Journal of Korean Society of Endocrinology
2004;19(5):542-545
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus (SLE) is autoimmune disease that often develops antiphopholipid syndrome (APS). Lupus anticoagulant and anticardiolipin antibodies are the hallmarks of APS. The hypercoagulable state in APS may lead to adrenal vein thrombosis, and subsquently lead to hemorrhagic necrosis of the adrenal gland. Adrenal hemorrhage is a very rare complication of APS. Although there have been some reports about adrenal hemorrhage associated with primary APS, adrenal hemorrhage associated secondary APS in SLE has not yet been reported. We describe the adrenal hemorrhage associated with secondary APS in SLE, and the patient which complained of general weakeness, nausea, vomiting and diffuse abdominal pain. Abdominal magnetic resonance imaging (MRI) showed hemorrhage, of both renal glands, and clinical features and immunological studies were consistent with APS in SLE. The acute adrenal insufficiency was much improved after the patient was treated with glucocorticoids
