Cutis Verticis Gyrata and Alopecia Areata: A Synchronous Coincidence?.
10.3349/ymj.2010.51.4.612
- Author:
Kwang Ho YOO
1
;
Jin Woong LEE
;
Woo Sun JANG
;
Kapsok LI
;
Seong Jun SEO
;
Chang Kwun HONG
Author Information
1. Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea. drseo@hanafos.com
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Alopecia areata;
cutis verticis gyrata;
fibroblast growth factor receptor 2 (FGFR2)
- From:Yonsei Medical Journal
2010;51(4):612-614
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cutis verticis gyrata (CVG) is a descriptive term for a scalp condition that is convoluted folds and deep furrows that resemble the surface of the cerebral cortex. It is categorized by the underlying etiology, as primary essential, primary non-essential and secondary. Alopecia areata (AA) is a common, organ specific autoimmune disease, and most AA cases are sporadic. There is clearly a strong genetic component. There is no established relationship between CVG and AA. We report one case which was affected with essential primary CVG and alopecia areata, and suggest a possibility of genetic association between CVG and AA, possibly both being related to mutations in the fibroblast growth factor receptor 2 (FGFR2).