A Case of Mycoplasma Pneumoniae Pneumonia Accompanying High Adenosine Deaminase Activity in Pleural Effusion.
- Author:
Hyang Eun SEO
1
;
Yeon Jae KIM
;
Seong Kyu KIM
;
Hyun Jae KANG
;
Yun Kyung DO
;
Hye Jin YOON
;
Jae Hyun CHYUN
;
Byung Ki LEE
;
Won Ho KIM
Author Information
- Publication Type:Case Report
- Keywords: Mycoplasma pneumoniae; Pleural effusion; Adenosine deaminase
- MeSH: Adenosine Deaminase*; Adenosine*; Cell Wall; Humans; Immunity, Cellular; Mycoplasma pneumoniae*; Mycoplasma*; Pleural Effusion*; Pneumonia*; Pneumonia, Mycoplasma*; Polymerase Chain Reaction; Serologic Tests; T-Lymphocytes
- From:Tuberculosis and Respiratory Diseases 2002;52(1):70-75
- CountryRepublic of Korea
- Language:Korean
- Abstract: Mycoplasma pneumioniae has a unique genomic composition, cellular biology, and a fastidious nature as the smallest cell-free living oranism that lacks a cell wall. Previous studies have suggested that a clinical manifesta tion of a M. pneumoniae infection is a consequence of a host immune response, particularly involving cellular immunity. Adenosine deaminase (ADA) is the main T-lymphocyte enzyme, and its activity is high in diseases where cellular immunity is stimulated. Therefore, its activity is useful for diagnosing a tuberculous pleural effusion. A pleural effusion is found in 5-20% of Mycoplasma pneumonia patients. However, there are few reports of high ADA activity in a mycoplasmal pleural effusion. Here we report a case of Mycoplasma pneumoniae infection established by a polymerase chain reaction and serologic tests, accompanying high ADA activity in a pleural effusion.
