Multifocal Osteosarcoma of the Skull: Multiple Primary or Metastatic? A Case Report.
- Author:
Hyuck CHO
1
;
Bong Jin PARK
;
Yong Koo PARK
Author Information
1. Department of Pathology, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea. ykpark@khmc.or.kr
- Publication Type:Case Report
- Keywords:
Osteosarcoma;
Skull;
Multifocal
- MeSH:
Drug Therapy;
Female;
Follow-Up Studies;
Headache;
Heart;
Humans;
Middle Aged;
Osteoblasts;
Osteosarcoma*;
Pathology;
Rabeprazole;
Skull*
- From:Korean Journal of Pathology
2014;48(2):146-150
- CountryRepublic of Korea
- Language:English
-
Abstract:
Osteosarcoma of the skull is a very rare condition. Moreover, it is extremely rare for osteosarcoma to present as multiple lesions confined to the skull. A 58-year-old woman was admitted with two masses in the parietal area of the skull, accompanied by mild headache and tenderness. Imaging revealed two masses with a heterogeneous consistency in the cranial bones. Excision craniectomy was performed and the pathology was consistent with osteoblastic osteosarcoma. Two nodules in the heart were found on routine follow-up imaging while the patient was undergoing chemotherapy. The nodules were biopsied and found to be metastatic osteosarcoma.