Staphylococcal Endocarditis Presenting with a Renal Infarct in a Patient with Acute Lymphoblastic Leukemia.
- Author:
Meong Hi SON
1
;
Eun Sil PARK
;
Ji Hyun SEO
;
Jae Young LIM
;
Chan Hoo PARK
;
Hyang Ok WOO
;
Hee Shang YOUN
Author Information
1. Department of Pediatrics, Gyeongsang National University College of Medicine, Jinju, Korea. espark@gsnu.ac.kr
- Publication Type:Case Report
- Keywords:
Precursor cell lymphoblastic leukemia-lymphoma;
Staphylococcus aureus;
Vegetation;
Coagulation
- MeSH:
Abscess;
Anti-Bacterial Agents;
Central Venous Catheters;
Doxorubicin;
Echocardiography;
Endocarditis;
Fever;
Flank Pain;
Follow-Up Studies;
Heparin;
Humans;
Induction Chemotherapy;
Maintenance Chemotherapy;
Mitral Valve;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Prednisolone;
Staphylococcus aureus;
Vincristine
- From:Cancer Research and Treatment
2008;40(3):151-154
- CountryRepublic of Korea
- Language:English
-
Abstract:
We present here a patient with acute lymphoblastic leukemia (ALL) and who developed infective endocarditis during induction chemotherapy with prednisolone, L-asparaginase (Leunase(R)), vincristine and adriamycin. The patient did not have a history of a central venous catheter. Sharp flank pain and fever occurred on the 25th day of induction chemotherapy. In addition, a renal infarct and movable vegetations on the mitral valve were detected on the abdominal computed tomography (CT) and echocardiography. S. aureus was identified in the cultured blood. While the patient achieved remission, follow-up echocardiography revealed the vegetation had in-creased in size and an abscess pocket had developed despite the antibiotics and heparin therapy. Consequently, ten days after the diagnosis of infective endocarditis, a successful mitral valvuloplasty was performed without complications. The patient is currently on maintenance chemotherapy while in remission.
