An Analytic Study for Incidence of Childhood Leukemia in Pusan City, Korea.
- Author:
Soon Yong LEE
1
;
Jong Bum SHIN
;
Ick Ho SUNG
;
Jae Sun PARK
;
Young Ho LEE
;
Young Tak LIM
;
Jin Ho CHUN
;
Kil Seo KIM
;
Sung Won KIM
;
Sung Taek KIM
;
Heui Jin KIM
;
Byung Do NAM
;
Soon Ok BYUN
;
Jin Kil PARK
;
Son Sang SEO
;
Young Suk JEON
;
Kyong Suk CHO
;
So Young HUH
Author Information
1. Department of Pediatrics, Inje University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Pusan city;
Childhood leukemia;
ALL;
AML;
CML;
Age and sex adjusted annual incidence rate;
Standardized annual incidence rate
- MeSH:
Bone Marrow Examination;
Busan*;
Female;
Hospitals, General;
Hospitals, University;
Humans;
Incidence*;
Korea*;
Leukemia*;
Male;
Mortality;
United States
- From:Korean Journal of Pediatric Hematology-Oncology
1998;5(1):81-88
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Cancer is the second cause of childhood death following accident, and leukemia is the most frequent childhood cancer in Korea. For the desirable control of childhood leukemia, of which the mortality is still high, the basic data for the incidence has a great importance. This is the second report from the data during 1991~1995 following the first one that analyzed the data from 328 cases of childhood leukemia during 1981~1990 in the same area, Pusan city, Korea. METHODS: The data were obtained from 138 new cases(84 males and 54 females from 0 to 15 years old) of childhood leukemia who had been living in the city of Pusan and were admitted to the 4 university hospitals and 11 general hospitals from 1991 to 1995. The cases were confirmed by CBC and bone marrow examination. RESULTS: The crude annual incidence rate per 100,000 population varied 1.50~5.30, 2.59~6.00 and 1.58~2.61 in the age group of 0~4 years, 5~9 years and 10~14 years, respectively. The standardized annual incidence rate per 100,000 population varied from 2.05 to 3.46(male 2.96~4.89, female 0.98~3.57). Sex ratio(male to female) was 1.58:1, 1.44:1, and 1.82:1 in total cases, ALL and AML, respectively, while incalculable in CML. By the major types of childhood leukemia, the cases were composed of 105 ALL (76.1%), 31 AML(22.5%), 2 CML(1.4%). CONCLUSION: It was concluded that the annual incidence rate of childhood leukemia per 100,000 population in Pusan city during 1991~1995 was similar to that of previous report during 1981~1990, while the proportion of ALL had tendency to increase up to that of United States, in contrast to the low proportions of ALL in the previous reports.
