Current Concept and New Strategy in Osteosarcoma Management.
10.5124/jkma.2006.49.12.1119
- Author:
Jae Do KIM
1
Author Information
1. Department of Orthopaedic Surgery, Kosin University College of Medicine, Korea. jdkim@ns.kosinmed.or.kr
- Publication Type:Original Article
- Keywords:
Osteosarcoma;
Current therapy;
Survival;
New strategy
- MeSH:
Diagnostic Imaging;
Drug Resistance;
Drug Therapy;
Humans;
Neoplasm Metastasis;
Osteosarcoma*
- From:Journal of the Korean Medical Association
2006;49(12):1119-1125
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Major progress in the management of osteosarcoma has been made due to advances in diagnostic imaging, operative technique, and chemotherapy, resulting in an improved survival. However, 20~30% of patients with osteosarcoma still develop distant metastases despite combined modality treatment. Currently various experimental efforts are being proposed to the future new strategy include drug resistance, suppression of metastasis mechanism, and targeted therapy to convert the incurable rate of 20~30% upto complete cure rate.
