Hypersensitivity to Mosquito Bites Associated with Natural Killer Cell-derived Large Granular Lymphocyte Lymphocytosis: A Case Report in Korea.
- Author:
Joo Seop CHUNG
1
;
Ho Jin SHIN
;
Eun Yup LEE
;
Goon Jae CHO
Author Information
1. Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.
- Publication Type:Case Report
- Keywords:
Hypersensitivity;
Mosquito bites;
Natural killer cell;
Large granular lymphocyte lymphocytosis
- MeSH:
Adult;
Animals;
Base Sequence;
*Culicidae;
Epstein-Barr Virus Infections/*complications/diagnosis;
Humans;
Hypersensitivity/*etiology/virology;
Insect Bites and Stings/*complications/immunology;
Killer Cells, Natural/*immunology/pathology;
Korea;
Lymphocytosis/*complications/pathology;
Male;
Molecular Sequence Data;
Polymerase Chain Reaction;
Prognosis;
Risk Assessment
- From:The Korean Journal of Internal Medicine
2003;18(1):50-52
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hypersensitivity to mosquito bites (HMB) is characterized by intense skin reactions at bite sites. The pathogenesis of HMB might be related to clonal lymphoproliferation of Epstein-Barr virus DNA-positive natural killer (NK) cells. We report the first case of HMB possibly associated with NK cell-derived large granular lymphocyte (NK-LGL) lymphocytosis in Korea.