A Case of Acropustulosis of Infancy.
- Author:
Young Chul JUNG
;
Ki Ho LEE
;
Choong Rim HAW
;
Jai Il YOON
;
Soo Duk LIM
- Publication Type:Case Report
- MeSH:
Anti-Bacterial Agents;
Bacteria;
Biopsy;
Dapsone;
Extremities;
Female;
Fingers;
Fungi;
Humans;
Infant;
Neutrophils;
Skin;
Skin Diseases
- From:Korean Journal of Dermatology
1983;21(2):195-199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acropustulosis of infancy is an uncommon, but not rare syndrome established as a new disease entity by Kahn and Rywlin(1976), which is characterized by recurrent, intensely pruritic vesicopustules on the distal extremities. We'd like to report a case of acropustulosis of infancy. Our patient was 19 month old girl who had been suffering from her skin disease since the age of 12 months. Intensely pruritic, 1 to 2 mm vesicopustules erupted on the palms, soles and the ventral aspects of the fingers. There were no bacteria, fungus and parasites(Sarcoptes scabiei) on the pustular lesions. Histopathologically, biopsy specimen of the left sole revealed large, well circumscribed intraepidermal pustule which was filled wth polymorphonuclear leukocytes. We confirmed our case as typical case of acropustulosis of infancy by it's characteristic clinical features and histopathologic findings. Severity of the skin lesions seems closely related to the dosage of dapsone. The eruptions were unresponsive to topical steroid, antibiotics and antihistaminics. But we observed that dapsone has dose dependent relationship with acropustulosis of infancy.
