A Case of Anti-Xga Antibody.
- Author:
Mi Na HUR
1
;
Kyu Man LEE
;
Jong Hyun KIM
;
Kyoung Un PARK
;
Eun Young SONG
;
Kyou Sup HAN
Author Information
1. Departments of Clinical Pathology, Hallym University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
anti-Xga;
unexpected antibody;
specificity;
transfusion
- MeSH:
Acute Kidney Injury;
Body Surface Area;
Bromelains;
Burns;
Erythrocytes;
Hemorrhage;
Humans;
Isoantibodies;
Male;
Middle Aged;
Phenotype;
Sensitivity and Specificity;
Ulcer
- From:Korean Journal of Blood Transfusion
2001;12(2):257-261
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anti-Xga is a rarely occurring antibody, and only two cases with this antibody have been reported in Koreans. We describe here another example of anti-Xga which was detected in a 47-year-old male. The patient suffered from burn injury on the 20% of body surface area, acute renal failure, and ulcer bleeding. Unexpected antibody identification test demonstrated anti-Xga, which was reactive only by antiglobulin phase, and the reaction disappeared after the treatment with bromelin. The red cell phenotype of this patient was Xg(a-). Fourteen units of packed red blood cell were transfused without any adverse reactions. It has an important clinical concern in safe transfusion practice to determine the specificity and the clinical significance of blood group alloantibodies.
