Neurotoxic Manifestations of an Overdose Intrathecal Injection of Gadopentetate Dimeglumine.
10.3346/jkms.2010.25.3.505
- Author:
Kwan Woong PARK
1
;
Soo Bin IM
;
Bum Tae KIM
;
Sun Chul HWANG
;
Jong Sun PARK
;
Won Han SHIN
Author Information
1. Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. isbrzw@sch.ac.kr
- Publication Type:Case Reports
- Keywords:
Neurologic Manifestations;
Injections, Spinal;
Gadolinium DTPA
- MeSH:
Adult;
Aphasia/etiology/pathology/physiopathology;
Brain/drug effects/pathology;
*Contrast Media/administration & dosage/toxicity;
*Gadolinium DTPA/administration & dosage/toxicity;
Humans;
*Injections, Spinal;
Male;
Muscle Rigidity/etiology/pathology/physiopathology;
*Neurotoxicity Syndromes/etiology/pathology/physiopathology;
Tomography, X-Ray Computed;
Vision Disorders/etiology/pathology
- From:Journal of Korean Medical Science
2010;25(3):505-508
- CountryRepublic of Korea
- Language:English
-
Abstract:
The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However, the general safety of intrathecal GD has not been established. We report a very rare case of an overdose intrathecal GD injection presenting with neurotoxic manifestations, including a decreased level of consciousness, global aphasia, rigidity, and visual disturbance.
