General Anesthesia for the Management of Status Epilepticus Refractory to Conventional Drugs: A case report.
10.4097/kjae.1998.35.2.360
- Author:
Jeong Suk KIM
1
;
Young Saeng KIM
;
Sung Du CHO
;
Nam Woen SONG
Author Information
1. Department of Anesthesiology, Maryknoll Hospital, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Anesthetics, volatile: isoflurane;
Anticonvulsants: phenobarbital;
phenytoin;
Seizure: status epilepticus
- MeSH:
Anesthesia, General*;
Anticonvulsants;
Blood Pressure;
Diazepam;
Dopamine;
Female;
Heart Rate;
Humans;
Isoflurane;
Pentobarbital;
Phenobarbital;
Phenytoin;
Seizures;
Status Epilepticus*;
Valproic Acid;
Ventilators, Mechanical;
Weaning
- From:Korean Journal of Anesthesiology
1998;35(2):360-364
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 2.5-year-old female patient who has a prior history of partial seizures was admitted by generalized tonic-clonic status epilepticus secondary to tapering of phenobarbital. Tonic-clonic status epilepticus was refractory to phenytoin, phenobarbital, valproic acid, diazepam, and pentobarbital. After 4 days of unsatisfactory control of seizure activity, isoflurane was administered for 4 hours. Inspired isoflurane concentration of 1.3% were required to control seizures. Heart rate and blood pressure were supported with infusions of dopamine and fluid. After discontinuation of isoflurane, the patient developed partial seizures but seizure activity was controlled with anticonvulsants. She was discharged alive from the hospital after weaning of the ventilator.
